Abstract
Utilizing a novel processing method of PEEK foam that produces hierarchical mesoporosity, we explore the use of hydroxyapatite (HA)/PEEK composites for mimicking the structure of human bone. The effect of HA content and processing parameters on the porosity, and interconnective network are studied with respect to the corresponding morphology, mechanical properties, and ultimately the cell viability. Having achieved hierarchical structuration with pore sizes ranging from approx. a hundred nanometers all the way to a few hundred microns, the HA/PEEK composites produced desirable mechanical properties and promising cell proliferation. A strong correlation was not seen with HA loading and the resulting properties, but a combination of the HA loading and variance in porosity is shown to be significant. The development and analysis of this bone mimic structure opens up the potential for this processing method and material as a treatment to bone injuries and bone diseases.
Published Version
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