Microstructure evolution of laser skin tissue welding under the control of energy regulation

Abstract

Laser skin tissue welding has the advantages of shallow scar and fast recovery due to the use of laser energy to suture skin tissue, and has great application potential in the field of beauty and biomedicine. However, the faster the recovery speed after surgery, the smaller the degree and scope of protein denaturation required, and the suture strength cannot be guaranteed, which makes it difficult to achieve both strength and recovery speed at the same time. Therefore, a laser targeted suture method based on energy regulation is proposed. This method can accurately control the region and extent of protein denaturation, and achieve the highest strength suture under the minimum protein denaturation. In addition, the directional fusion of collagen reticular tissue was achieved by regulating the micro morphology of denatured collagen tissue during the suturing process, and the suture samples meeting the requirements were successfully obtained. The microstructure observation and mechanical property test of the adjusted suture sample showed that the re melted collagen fiber tissue was reticular distribution, similar to the original tissue structure, with good mechanical properties, and the tensile strength reached 41.6 ± 2.5 N/cm2. This makes this method have a great potential application prospect in biological tissue welding application scenarios.