Abstract

Microsphere is one the novel technology that is used to deliver the drug to it targeted site. Microsphere they are micro particle in size. They are of natural and synthetic one. There are various approaches in delivering a therapeutic substance to the target site in a sustained controlled release fashion. For preparation of microsphere protein physiochemical property to be optimized this include optimal pH, protein stochiometry and protein concentration. Some of the important microsphere technology includes Ceformin microsphere technology Ceformin EI, Ceformin TI, Ceformin EA/CR, Silk microsphere and gelatin microsphere. Microsphere drug delivery system has gained enormous attention due to its wide range of application as it covers targeting the drug to particular site to imaging and helping the diagnostic features. Microsphere is excellent polymer used for buccal delivery. It is also used to deliver pacilitaxel at the tumor site. In the present study valuable and selective information on microsphere is enlightened with its important applications which will be beneficial for further newer drug development.

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