Abstract
A model Hamiltonian for double-strand polynucleotides is suggested to describe the phenomenon of helix–coil transition. The Hamiltonian is constructed using solely the microscopical, pure physical quantities, characterizing the molecular chain, namely the energy of hydrogen-bond formation and the number of conformations of repeated unit. Realistic constraints are imposed on the conformations of chain in the case of loop formation. The advantage of the suggested approach is that the parameters of the model can be obtained from independent calculations or experiments. It is shown that with the approximation of neglecting the effect of large loops, the model of DNA is reduced to the generalized microscopical model of polypeptide chain.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Physica A: Statistical Mechanics and its Applications
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
