Abstract
Microporous foams of polymer blends of two biodegradable polyesters, poly(L-lactic acid) (PLLA) and poly(ε-caprolactone) (PCL), were prepared via thermally induced phase separation method. The phase behaviors of the solutions of the polymer blends in 1,4-dioxane containing water were similar, which would be due to the similar solubility parameters of the two polymers (20.5–21.1 and 21.2 MPa 0.5). However, the porous structure of the polymer blends dependent on the blend ratio under the same conditions other than the ratio. Hepatic cells (HepG2 cells) were cultured on the porous polymer blends. The cells invaded into the scaffold of PCL and PLLA–PCL-blend (1:4) by 1.0 and 1.5 mm, respectively, while they grew near the surface of the PLLA foams. Blending of biodegradable polyesters has the potential of controlling the porous structure of biodegradable foams.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
