Abstract
Substrate supported planar lipid bilayers (SPBs) are versatile models of the biological membrane on solid substrates. We have developed a methodology for generating SPBs composed of polymeric and fluid phospholipid bilayers by using a photo-polymerizable diacetylene phospholipid (DiynePC).(1) Polymeric bilayers could be generated with micro-patterns by the conventional photolithography, and the degree of polymerization could be controlled by modulating UV irradiation doses.(2)(3) After removing non-reacted monomers, fluid lipid membranes could be integrated with polymeric bilayers.
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