Abstract

As a new apparatus for bioseparation, a PDMS (polydimethylsiloxane) microchip for capillary gel electrophoresis that can separate different sizes of biomolecules in a small and simple experimental scale is presented. The chip was made by microfabrication technology and the micro-capillary structures on the microchip were partially filled with agarose gel that can enhance separation resolution. Biomolecules such as DNA molecules were successfully driven by electric field and separated to form bands in the agarose-filled microstructures.

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