Abstract
Introduction. Capillary changes link are closely correlated with shifts in central hemodynamics, which allows the use of microcirculation parameters as diagnostic and prognostic criteria for assessing the body as a whole. The work is aimed at increasing the efficiency of detecting microcirculatory disorders by computer capillaroscopy in patients with pathology of intranasal structures and accompanied by difficulty in nasal breathing and smell. Purpose: nature and severity analysis of intravital morphological changes in the microvessels of the nail bed in patients with pathology of the intranasal structures, accompanied by impaired nasal breathing and smell.Materials and methods: We examined 145 patients aged 18–38 years who were diagnosed with changes in intranasal structures with varying degrees of nasal obstruction and impaired sense of smell. Patients were divided into 3 groups. The first group — patients with a disease duration of 3–5 years; the second group — patients with a disease duration of up to 0.5 years; the third group — patients with a disease duration of up to 1 month. Results: Patients with intranasal structures pathology in the I and III clinical groups with a duration of nasal obstruction up to 5 years and 1 month. Changes in systemic microcirculation were significantly more frequently observed than in patients with a disease duration of up to 0.5 years. The observed tendency to disturbance of microcirculation in groups III and I is caused, first of all, by a change in the state of microvessels for sharp hypoxia (these changes are consistent with rhinomanometry) and a “breakdown” of adaptation mechanisms in the group of prolonged nasal obstruction for up to 5 years, at that time as in group II, there is an increase in the reserve of adaptation from the cardiovascular system to the conditions of nasal obstruction. Сonclusions: The study of microcirculation using capillaroscopy made it possible to study the smallest vessels, capillaries, which are the first to respond to impaired nasal breathing by changing the functional state and morphological reconstruction of the microvasculature of the bloodstream.
Highlights
Capillary changes link are closely correlated with shifts in central hemodynamics, which allows the use of microcirculation parameters as diagnostic and prognostic criteria for assessing the body as a whole
The work is aimed at increasing the efficiency of detecting microcirculatory disorders by computer capillaroscopy in patients with pathology of intranasal structures and accompanied by difficulty in nasal breathing and smell
Materials and methods: We examined 145 patients aged 18–38 years who were diagnosed with changes in intranasal structures with varying degrees of nasal obstruction and impaired sense of smell
Summary
Работа направлена на повышение эффективности выявления микроциркуляторных нарушений методом компьютерной капилляроскопии у больных с патологией внутриносовых структур и сопровождающимся затруднением носового дыхания и обоняния. Цель: анализ характера и выраженности прижизненных морфологических изменений микрососудов ногтевого ложа у больных с патологией внутриносовых структур, сопровождающимися нарушением носового дыхания и обоняния. Обследовано 145 больных в возрасте 18–38 лет, у которых диагностированы изменения внутриносовых структур с различной степенью назальной обструкции и нарушением обоняния. У больных с патологией внутриносовых структур в I и III клинических группах с продолжительностью носовой обструкции до 5 лет и 1 мес. Изучение микроциркуляции с помощью капилляроскопии позволила исследовать наименьшие сосуды, капилляры, которые первыми реагируют на нарушение носового дыхания путем изменения функционального состояния и морфологической перестройки микрососудов кровеносного русла. Ключевые слова: микроциркуляторное русло, внутриносовые структуры, нарушение носового дыхания и обоняния
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