Mhc Genes In Invertebrates: The Echinodermata

Michel Leclerc,Pierre De La Grange,Ariane Jolly

doi:10.15226/2473-2176/4/1/00131

Abstract

Mhc Genes In Invertebrates: The Echinodermata

Highlights

For the first time major histocompatibility complex (MHC) ClassII gene was described in Echinodermata, so in Invertebrates
Since we have discovered the IPA (Invertebrate Primitive Antibody), to acquire a better understanding of the invertebrate immune system, it seemed useful to look for MHC genes(HLADRB1 gene)(HLA-C gene) in invertebrates with Ophiocomina nigra (Ophuirids), Antedon bifida (Crinoïds) as model of studies
Blasts against Human were performed and, MHC gene Class II appears in the genome of Ophiocomina nigra and Antedon bifida one, in a significant manner

Summary

Introduction

For the first time MHC ClassII gene was described in Echinodermata, so in Invertebrates. For the present time MHC ClassI gene was not found in a significant manner (e-value no significant) but further studies are necessary to conclude about its existence in Echinodermata. To day, these studies lead us to envisage with confidence this research. The term polymorphism comes from the Greek poly, meaning many, and morphe, meaning shape or structure As used here, it means within-species variation at a gene locus, and in its protein product; the variant genes that can occupy the locus are termed alleles. The extensive polymorphism at each locus has the potential to double the number of different MHC molecules expressed in an individual and thereby increases the diversity already available through polygeny

Methods

Results

Conclusion