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https://doi.org/10.1016/j.chembiol.2024.03.005
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Cite Journal: Cell Chemical Biology |  Publication Date: Apr 18, 2024 |
The tumor microenvironment (TME) dictates the outcome of cancer immunotherapy. In this issue of Cell Chemical Biology, Yu etal.1 report that targeting Mettl3 leads to a more inflamed, "hot" TME and effective anti-PD-1 therapy. This study points to a new target in remodeling the TME for improved immunotherapy.
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