Abstract
In the isoquinoline ring system of the title molecule, C19H22N2O5, the N-heterocyclic ring is in a half-boat conformation. The dioxa-2-azaspiro ring is essentially planar [maximum deviation = 0.042 (1) Å] and forms a dihedral angle of 81.85 (4)° with the benzene ring. In the crystal, the molecules are linked via intermolecular C—H⋯O hydrogen bonds into chains along [010].
Highlights
In the isoquinoline ring system of the title molecule, C19H22N2O5, the N-heterocyclic ring is in a half-boat conformation
Isoquinolines are often found in bioactive natural products
Oxazole rings are found in some bioactive natural products such as Annuloline and Ostreogrycin A
Summary
USM, Penang, Malaysia, and bSchool of Chemistry and Chemical Engineering, Nanjing University, Nanjing, 210093, People’s Republic of China. R factor = 0.039; wR factor = 0.113; data-to-parameter ratio = 26.0. In the isoquinoline ring system of the title molecule, C19H22N2O5, the N-heterocyclic ring is in a half-boat conformation. The dioxa-2-azaspiro ring is essentially planar [maximum deviation = 0.042 (1) Å] and forms a dihedral angle of 81.85 (4) with the benzene ring. The molecules are linked via intermolecular C—H O hydrogen bonds into chains along [010]
Sign-in/Register to view highlights & summary 
Published Version (
Free)
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call