Methods for the determination of organochlorine pesticide residues in human serum

Abstract

The effectiveness of solid-phase extraction with Florisil for the determination of 12 organochlorine pesticide residues from human serum was examined. Recoveries greater than 84% and coefficients of variation better than 19% were obtained. Others methods, such as column partition and matrix solid-phase dispersion, were compared. The better method provides quantification limits ranging from 1.08 μg/l for γ-HCH and 37.5 μg/l for p, p′-DDT when capillary gas–liquid chromatography with electron-capture detection is used for the final determination.