Abstract
Histological sections of the organ of Corti show in some cases a very pronounced outward bending of Reissner's membrane and in other cases just the opposite, namely, an inward bending. This has brought up the question of whether or not a disease of the inner ear may produce a pressure variation in the endolymphatic duct. If such a pressure variation were present, it should show up in the chemical content of the endolymphatic fluid. Interest in this question was enhanced by the findings of Smith 1 and Smith, Lowry, and Wu, 2 who found that the chemical constitution of the endolymph is quite different from the constitution of other body fluids. The question today is this: Are innerear diseases a consequence of changes in the chemistry of the endolymph or are inner-ear diseases rather produced by changes in the cell structure of the organ of Corti? A differentiation of the
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