Abstract
Hospital Associated infections are on the rise globally. Methicillin-resistant Staphylococcus aureus (MRSA) is one of the common pathogens resulting in increased morbidity and mortality among orthopedic patients. Though individual reports are available, no systematic review on the prevalence of MRSA infection among orthopedic patients in South-East Asia Region (SEAR) is accessible and hence, the systematic review and meta-analysis is conducted. We systematically searched eight databases (Scopus, PubMed-Medline, IndMed, CINAHL, Proquest, Web of Science, Ovid-Medline, and Google-Scholar) and included the articles published from 2006 to 2019 from SEAR. A total of 22 studies were eligible for the review. STATA 13.0 with metaprop package in STATA was used to find the rate of MRSA infection. Among 1135 orthopedic patients, the pooled prevalence of MRSA infection was 27% (95% confidence interval 17%–38%; P = 0.001, I2 95.99%). Based on this infection rate, the policymakers are recommended to develop guidelines to effectively manage infection in healthcare settings to reduce the burden of MRSA infection among orthopedic patients.
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