Abstract
Rectal leiomyosarcoma is a very rare tumor with a poor prognosis. We report the clinical case of a 45-year-old patient who presented with an externally palpable mass during defecation, accompanied by mild rectal bleeding. Colonoscopy revealed an ulcerated, budding, hemorrhagic, semi-circumferential rectal tumor. An anatomopathological examination with immunohistochemical study confirmed the diagnosis of leiomyosarcoma. The staging showed multiple secondary liver lesions. The case was discussed in a multidisciplinary meeting, and the decision was made to initiate first-line chemotherapy. However, the patient passed away before the treatment could commence.
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