Abstract
Hepatocellular carcinoma is a common primary hepatic malignancy in the Asian countries. The prognosis of metastatic hepatocellular carcinoma is very poor if left untreated. Despite the rare occurrence, sinonasal metastasis of hepatocellular carcinoma usually implies an advanced disease stage with dismal outcome. Herein we present a case of metastatic hepatocellular carcinoma involving the nasal cavity. This 55-year-old male patient refused standard therapy after the diagnosis of hepatocellular carcinoma. After a palliative excision for the nasal tumor, the patient died of multiple metastatic diseases. A special consideration should be given to such unusual manifestations of extrahepatic metastases. Promptly clinical evaluation and appropriate intervention for symptomatic palliation are necessary for these terminally ill patients.
Highlights
Metastatic tumors are rarely encountered in the nasal cavity
Sinonasal region is an unusual site for metastatic hepatocellular carcinoma (HCC), and there are only two reported cases with solely nasal metastases [2,6]
The high incidence in Asia is due to the high prevalence of chronic viral hepatitis, chronic hepatitis B
Summary
Metastatic tumors are rarely encountered in the nasal cavity. Sinonasal region is an unusual site for metastatic hepatocellular carcinoma (HCC), and there are only two reported cases with solely nasal metastases [2,6]. We report an additional case of metastatic HCC to the nasal cavity. Our case demonstrates disseminated diseases after the appearance of nasal tumor.
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