Abstract
Pseudocirrhosis describes morphological changes in the liver that resemble cirrhosis, but the histopathological findings are not suggestive of cirrhosis. It occurs most often in patients with metastatic breast cancer, although it has also been reported in other malignancies. As in cirrhosis, portal hypertension is often seen in patients with pseudocirrhosis. Pseudocirrhosis is a rare but important complication of metastatic cancer. We will describe the case of a 45-year-old woman with a history of breast cancer, without any previously known liver disease presenting with subacute liver failure. Initial imaging studies indicated cirrhosis of the liver without signs of focal malignancy. Full diagnostic workup was negative for specific causes of liver disease and provided no evidence of tumor recurrence. Malignant pseudocirrhosis is an unusual type of metastatic tumor, with spread representing a rare but important differential diagnosis of progressive liver failure.
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