Abstract
Meningiomas are the most common extra-axial central nervous system tumours and often discovered in the middle to late adult life and especially in women. About 85%-90% of meningiomas are benign, 5%-10% are intermediate-grade, and 3%-5% are malignant. Metaplastic meningioma is a rare subtype of WHO Grade I meningioma histologically characterized by the presence of mesenchymal components. The presence of pure and extensive cartilaginous differentiation in meningiomas is extremely rare and remains a diagnostic dilemma. We report, perhaps the first case of this entity in a 52-year-old woman and discuss the pathogenesis, the imaging features and the histopathologicals data.
Highlights
INTRODUCTIONMeningiomas are the most extra-axial central nervous system tumours and often discovered in the middle to late adult life, especially in women, and account approximately 15% - 30% of all intracranial tumors [1]
Meningiomas are the most extra-axial central nervous system tumours and often discovered in the middle to late adult life, especially in women, and account approximately 15% - 30% of all intracranial tumors [1]. They are classified into three groups according to the World Health Organisation (WHO) grading system based upon morphologic criteria with characteristic pathologic and imaging features: benign meningiomas in 85% - 90% (WHO grades of malignancy: typical or benign meningiomas (Grade I)), atypical meningiomas in 5% - 10%
Metaplastic meningioma is a rare subtype of WHO Grade I meningioma histologically characterized by the presence of mesenchymal components, including osseous, cartilaginous, lipomatous, myxoid or xanthomatous and cartilaginous tissue [3]
Summary
Meningiomas are the most extra-axial central nervous system tumours and often discovered in the middle to late adult life, especially in women, and account approximately 15% - 30% of all intracranial tumors [1]. They are classified into three groups according to the World Health Organisation (WHO) grading system based upon morphologic criteria with characteristic pathologic and imaging features: benign meningiomas in 85% - 90% (WHO Grade I), atypical meningiomas in 5% - 10%. We discuss the diagnostic dilemma in this kind of meningioma
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