METACHRONOUS CALCIFYING EPITHELIAL ODONTOGENIC TUMOR WITH LONG-TERM FOLLOW-UP

Abstract

This is a description of an extremely rare metachronous presentation of calcifying epithelial odontogenic tumor (CEOT) in a 52-year-old woman with a history of synchronous tumors 12 years earlier. The patient presented 2 peripheral CEOTs that appeared clinically as bilateral gingival swellings between the lower first premolar and canine. Both tumors recurred and an additional surgical removal was performed, with no recurrences observed after 3.5 years of follow-up. Eight years after the last consultation, the patient complained of an asymptomatic normochromic nodule of 2.5 cm in the lower posterior gingiva, causing saucerization of the alveolar cortical bone between the second premolar and first molar; the location ruled out the possibility of late recurrence. The diagnosis of CEOT was confirmed microscopically, with no additional tumor after 2 years. Long-term follow-up is recommended for patients with multiple CEOTs for better comprehension of this unique clinical presentation.