Peripheral Calcifying Epithelial Odontogenic Tumor Associated With Generalized Drug-Induced Gingival Growth: A Case Report

Abstract

Calcifying epithelial odontogenic tumor (CEOT) or Pindborg tumor is a rare, benign neoplasm of odontogenic origin, which accounts for about 0.4% to 3% of all odontogenic tumors. 1 Philipsen H.P. Reichart P.A. Calcifying epithelial odontogenic tumor: Biological profile based on 181 cases from the literature. Oral Oncol. 2000; 36: 17 Abstract Full Text Full Text PDF PubMed Scopus (167) Google Scholar , 2 Cheng Y.L. Wright J.M. Walstad W.R. et al. Calcifying epithelial odontogenic tumor showing microscopic features of potential malignant behavior. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2002; 93: 287 Abstract Full Text Full Text PDF PubMed Scopus (40) Google Scholar This lesion was described as a distinct entity for the first time by Pindborg in 1955 and was designated as Pindborg tumor in 1967. 3 Houston G.D. Fowler C.B. Extraosseous calcifying epithelial odontogenic tumor Report of two cases and review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1997; 83: 577 Abstract Full Text PDF PubMed Scopus (50) Google Scholar , 4 Bouckaert M.M.R. Raubenheimer E.J. Jacobs F.J. Calcifying epithelial odontogenic tumor with intracranial extension: Report of a case and review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2000; 90: 656 Abstract Full Text Full Text PDF PubMed Scopus (37) Google Scholar Intraosseous location of the tumor is the most common, accounting for about 94% of the cases reported thus far, but an extraosseous or peripheral variant was also described by Pindborg in 1966 and corresponds to approximately 6% of all cases of CEOT. 3 Houston G.D. Fowler C.B. Extraosseous calcifying epithelial odontogenic tumor Report of two cases and review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1997; 83: 577 Abstract Full Text PDF PubMed Scopus (50) Google Scholar , 5 Takeda Y. Suzuki A. Sekiyama S. Peripheral calcifying epithelial odontogenic tumor. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1983; 56: 71 Abstract Full Text PDF Scopus (24) Google Scholar , 6 Mesquita R.A. Lotufo M.A. Sugaya N.N. et al. Peripheral clear cell variant of calcifying epithelial odontogenic tumor: Report of a case and immunohistochemical investigation. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2003; 95: 198 Abstract Full Text Full Text PDF PubMed Scopus (30) Google Scholar