Abstract
Homogenates of adult male guinea pig liver and kidney are able to metabolize testosterone to androstenedione. No other metabolites were detected. Optimum conditions for the action of the enzyme(s) have been determined in regard to amount of tissue, preparation of homogenate, cofactor, ph, duration of incubation and amount of steroid. The kidney differed from the liver in its response to the addition of nicotinamide and requirements of DPN. The activity of the tissues was quite high; 12 gm of either tissue under optimum conditions was able to convert approximately 50% of 50 mg of testosterone to androstenedione.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
