Metabolically Healthy Obesity and Development of Chronic Kidney Disease.

Abstract

Letters15 November 2016Metabolically Healthy Obesity and Development of Chronic Kidney DiseaseYoosoo Chang, MD, PhD, Seungho Ryu, MD, PhD, Juhee Cho, PhD, Roberto Pastor-Barriuso, PhD, and Eliseo Guallar, MD, DrPHYoosoo Chang, MD, PhDFrom Kangbuk Samsung Hospital and Sungkyunkwan University, Seoul, South Korea; Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland; and Carlos III Institute of Health and Consortium for Biomedical Research in Epidemiology and Public Health, Madrid, Spain.Search for more papers by this author, Seungho Ryu, MD, PhDFrom Kangbuk Samsung Hospital and Sungkyunkwan University, Seoul, South Korea; Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland; and Carlos III Institute of Health and Consortium for Biomedical Research in Epidemiology and Public Health, Madrid, Spain.Search for more papers by this author, Juhee Cho, PhDFrom Kangbuk Samsung Hospital and Sungkyunkwan University, Seoul, South Korea; Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland; and Carlos III Institute of Health and Consortium for Biomedical Research in Epidemiology and Public Health, Madrid, Spain.Search for more papers by this author, Roberto Pastor-Barriuso, PhDFrom Kangbuk Samsung Hospital and Sungkyunkwan University, Seoul, South Korea; Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland; and Carlos III Institute of Health and Consortium for Biomedical Research in Epidemiology and Public Health, Madrid, Spain.Search for more papers by this author, and Eliseo Guallar, MD, DrPHFrom Kangbuk Samsung Hospital and Sungkyunkwan University, Seoul, South Korea; Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland; and Carlos III Institute of Health and Consortium for Biomedical Research in Epidemiology and Public Health, Madrid, Spain.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/L16-0405 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail IN RESPONSE:We thank Drs. Stanford and Butsch, Drs. Kahn and Pavkov, and Dr. Little and colleagues for their interest in our study and for raising important points about the interpretation of our results. Several of the arguments address the use of Asian-specific cutoffs for BMI and the obesity paradox. For a given BMI, Asians have a higher percentage of total body fat (1) and a higher risk for cardiometabolic disease (2) than white persons. As a consequence, Asian Pacific–specific BMI criteria have gained widespread acceptance. As for more detailed analyses by degree of obesity, only 211 (0.3%) participants in ...