Metabolic effects of Cimicifuga racemosa extract Ze450 on neuronal cells

Abstract

Mitochondria are key regulators of energy metabolism and, therefore, an emerging focus of research on metabolic, neurodegenerative and other age-related diseases. Estrogen depletion is well known to induce common menopausal complaints; however, mounting evidence suggests additional effects, such as increasing oxidative stress which may contribute to the development of metabolic disorders [ [1] Sekhon, L.H., Agarwal, A., Humana Press, Totowa, NJ. 181-203. Google Scholar ].