Abstract

Menopause maybe associated with several short, medium and long-term consequences. Metabolic disturbances represent a significant negative effect of the progressive reduction of estradiol as well as of the increased androgens/estrogens ratio occurring during perimenopause (1). Besides, other hormonal (such as, hypercortisolism and/or altered thyroid function) or non-hormonal (family hystory, dietary habits, smoking, alcohol consumption, etc.) factors, could negatively impact on metabolism in an individualized manner. On the other hand, the ageing per se usually favours a change of body composition characterized by a reduction of lean body mass (LBM) and an increase of fat free mass (FFM), exposing post-menopausal women to higher cardiometabolic risk.

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