Metabolic characteristics of brain structures during conscious and unconscious anxiety

Abstract

Metabolic processes accompanying conscious and unconscious anxiety states in patients with multiple sclerosis were studied. The correspondence between glucose metabolism rates (evaluated using positron emission tomography images) and indices of conscious and unconscious anxiety (according to the Taylor and Luscher test scores) was estimated. Data on the specific features of brain activity at various levels of conscious and unconscious anxiety were obtained. The elevation of conscious anxiety was accompanied by an increase in the metabolic activity of the left-hemisphere cortical and subcortical structures, as well as by a decrease in the glucose metabolism rate in the majority of right-hemisphere structures (except limbic and thalamic structures). The elevation of unconscious anxiety was accompanied by a decrease in the rate of glucose metabolism in the left frontal structures, whereas in the amygdala, as well as in the other limbic structures (gyrus temporalis inferior), its rate increased.