Abstract
SummarySixteen obese women and two obese men were submitted to total fasting. During the first seven days the mean cumulative weight loss amounted to 6.33 kg (range : 2.9 - H.o kg). This decrease in weight was mainly due to losses of body fluids. When refeeding some of the patients with different types of hypocaloric diets, it appeared that glucose administration curtailed abruptly urinary sodium excretion, causing fluid retention and eventually a gain in body weight and the development of edema. This effect on bodily hydration was not seen when giving proteins (casein) or fat (butter). A review of the literature concerning the influence of dietary constituents on body fluid balance is given. The possible mechanisms of the sodium-retaining action of carbohydrates are discussed.
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