Metabolic activation of polycyclic hydrocarbons. Fluorescence spectral evidence is consistent with metabolism at the 1,2- and 3,4-double bonds of 7-methylbenz[a]anthracene.

Abstract

FEBS LettersVolume 75, Issue 1-2 p. 9-12 Full-length articleFree Access Metabolic activation of polycyclic hydrocarbons Fluorescence spectral evidence is consistent with metabolism at the 1,2- and 3,4-double bonds of 7-methylbenz[a]anthracene1 P. Vigny, P. Vigny Fondation Curie-Institut du Radium, Laboratoire Curie, 11, Rue Pierre et Marie Curie, 75231, Paris, Cedex 05, FranceSearch for more papers by this authorM. Duquesne, M. Duquesne Fondation Curie-Institut du Radium, Laboratoire Curie, 11, Rue Pierre et Marie Curie, 75231, Paris, Cedex 05, FranceSearch for more papers by this authorH. Coulomb, H. Coulomb Fondation Curie-Institut du Radium, Laboratoire Curie, 11, Rue Pierre et Marie Curie, 75231, Paris, Cedex 05, FranceSearch for more papers by this authorC. Lacombe, C. Lacombe Fondation Curie-Institut du Radium, Laboratoire Curie, 11, Rue Pierre et Marie Curie, 75231, Paris, Cedex 05, FranceSearch for more papers by this authorB. Tierney, B. Tierney Chester Beatty Research Institute, Institute of Cancer Research, Royal Cancer Hospital, Fulham Road, London SW3 6JB, EnglandSearch for more papers by this authorP.L. Grover, P.L. Grover Chester Beatty Research Institute, Institute of Cancer Research, Royal Cancer Hospital, Fulham Road, London SW3 6JB, England To whom correspondence should be addressed Search for more papers by this authorP. Sims, P. Sims Chester Beatty Research Institute, Institute of Cancer Research, Royal Cancer Hospital, Fulham Road, London SW3 6JB, EnglandSearch for more papers by this author P. Vigny, P. Vigny Fondation Curie-Institut du Radium, Laboratoire Curie, 11, Rue Pierre et Marie Curie, 75231, Paris, Cedex 05, FranceSearch for more papers by this authorM. Duquesne, M. Duquesne Fondation Curie-Institut du Radium, Laboratoire Curie, 11, Rue Pierre et Marie Curie, 75231, Paris, Cedex 05, FranceSearch for more papers by this authorH. Coulomb, H. Coulomb Fondation Curie-Institut du Radium, Laboratoire Curie, 11, Rue Pierre et Marie Curie, 75231, Paris, Cedex 05, FranceSearch for more papers by this authorC. Lacombe, C. Lacombe Fondation Curie-Institut du Radium, Laboratoire Curie, 11, Rue Pierre et Marie Curie, 75231, Paris, Cedex 05, FranceSearch for more papers by this authorB. Tierney, B. Tierney Chester Beatty Research Institute, Institute of Cancer Research, Royal Cancer Hospital, Fulham Road, London SW3 6JB, EnglandSearch for more papers by this authorP.L. Grover, P.L. Grover Chester Beatty Research Institute, Institute of Cancer Research, Royal Cancer Hospital, Fulham Road, London SW3 6JB, England To whom correspondence should be addressed Search for more papers by this authorP. Sims, P. Sims Chester Beatty Research Institute, Institute of Cancer Research, Royal Cancer Hospital, Fulham Road, London SW3 6JB, EnglandSearch for more papers by this author First published: March 15, 1977 https://doi.org/10.1016/0014-5793(77)80041-0Citations: 35 To whom correspondence should be addressed 1 The authors would like to dedicate this paper to the memory of Mme Pascaline Daudel who died in Paris on May 12th 1976 AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat References 1 P. Daudel, M. Croisy-Delcey, C. Alonso-Verduras, M. Duquesne, P. Jacquignon, P. Markovits, P. Vigny, C. R. Acad. Sci., 278, (1974), 2249– 2252. 2 P. Daudel, H. Kawamura, M. Croisy-Delcey, M. Duquesne, P. Jacquignon, C. R. Acad. Sci., 280, (1975), 521– 524. 3 P. Daudel, M. Duqesne, P. Vigny, P.L. Grover, P. Sims, FEBS Lett., 57, (1975), 250– 253. 4 J. Booth, P. Sims, FEBS Lett., 47, (1974), 30– 33. 5 P. Sims, P.L. Grover, A. Swaisland, K. Pal, A. Hewer, Nature, 252, (1974), 326– 328. 6 P.L. Grover, K. Pal, A. Hewer, P. Sims, Int. J. Cancer, 18, (1976), 1– 6. 7 P. Sims, Biochem. J., 105, (1967), 591– 598. 8 Tierney, B. and Sims, P. manuscript in preparation. 9 P. Sims, Biochem. Pharmacol., 19, (1970), 795– 818. 10 E.R.M. Kay, N.S. Simmons, A.L. Dounce, J. Am. Chem. Soc., 74, (1952), 1724– 1726. 11 P. Vigny, M. Duquesne, Photochem. Photobiol., 20, (1974), 15– 25. 12 W.M. Baird, A. Dipple, P.L. Grover, P. Sims, P. Brookes, Cancer Res., 33, (1973), 2386– 2392. 13 P.L. Grover, A. Hewer, P. Sims, Biochem. Pharmacol., 23, (1973), 323– 332. 14 Marquardt, H., Baker, S., Tierney, B., Grover, P. L. and Sims, P. (1977) submitted for publication. 15 Malaveille, C., Tierney, B., Grover, P. L., Sims, P. and Bartsch, H. (1977) submitted for publication. 16 Chouroulinkov, I. and Gentil, A. personal communication. Citing Literature Volume75, Issue1-2March 15, 1977Pages 9-12 ReferencesRelatedInformation