Abstract
Objective To identify the risk factors of postoperative delirium after cardiac surgery . Methods Setting the inclusion and exclusion criteria and establishing the retrieval strategies for primitive literatures, several databases were searched .The RevMan 4.3 software was adopted to perform the analysis of sensitivity and heterogeneity and to calculate the cumulative effects of risk factors using either fixed or random effects model .Results Fifteen studies were included in the final analysis .The independent risk factors of delirium after cardiac surgery were older age; history of artial fibrillation , diabetes mellitus , cerebrovascular disease , abnormal serum creatinine level , anemia and depression;valve replacement or combined procedure and prolonged operation time;prolonged mechanical ventilation time , massive use of sedative and postoperative atrial fibrillation.Conclusions The patients with a history of atrial fibrillation or with a complication of postoperative atrial fibrillation are at an increased risk of developing delirium following elective cardiac surgery .And the valve replacement or combined procedure and prolonged operation time are uniquely associated with postoperative delirium. Key words: Delirium; Risk factors; Cardiac surgery; Meta analysis
Published Version
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