Meta-Analysis of Jianpi Yiqi Combined with Glucocorticoid Therapy for Primary Thrombocytopenic Purpura

Abstract

A systematic review of the efficacy and safety of Jianpi Yiqi combined with glucocorticoids in the treatment of immune thrombocytopenic purpura. Randomized controlled trial of Jianpi Yiqi therapy combined with glucocorticoid therapy for immune thrombocytopenic purpura was retrieved without any restrictions on blindness and language. Randomized controlled trial that met the inclusion criteria were screened, and the Revman5.3 software was used for meta-analysis. A total of 27 articles were included with 1716 cases. The results of the meta-analysis showed that in terms of the effective rate of Western medicine, the effect of Jianpi Yiqi combined with glucocorticoid therapy were significantly better than that of glucocorticoid therapy alone, with a statistically significant difference (p<0.0001). The combination of traditional Chinese and Western medicine is better than hormone therapy in improving the efficiency of traditional Chinese medicine, platelet count, syndrome score, interleukin-10 and cluster of differentiation 4/cluster of differentiation 8 levels. The effect of Jianpi Yiqi combined with glucocorticoid in the treatment of immune thrombocytopenic purpura is better than that of glucocorticoid alone, which is worthy of further study and promotion.