Abstract
Purpose KiSS-1 and its product, kisspeptin is necessary for pubertal onset and proper adult gonadal function due to its stimulatory effect on the secretion of gonadotropinreleasing hormone (GnRH). Although the pathophysiological importance of KiSS-1 and kisspeptin is well known, the developmental patterns of expression of KiSS-1 genes and serum level of kisspeptin have not been explored to date. We report herein the expression profile of KiSS-1 genes and serum level of kisspeptin in the rat at different developmental stages.
Highlights
KiSS-1 and its product, kisspeptin is necessary for pubertal onset and proper adult gonadal function due to its stimulatory effect on the secretion of gonadotropinreleasing hormone (GnRH)
The pathophysiological importance of KiSS-1 and kisspeptin is well known, the developmental patterns of expression of KiSS-1 genes and serum level of kisspeptin have not been explored to date
We report the expression profile of KiSS-1 genes and serum level of kisspeptin in the rat at different developmental stages
Summary
Jung Min Ahn1*, Ah Reum Kwon[1], Hyun Wook Chae[1], Kyungchul Song[1], Duk Hee Kim[2], Ho-Seong Kim[1]. From 8th APPES Biennial Scientific Meeting Darwin, Australia. Purpose KiSS-1 and its product, kisspeptin is necessary for pubertal onset and proper adult gonadal function due to its stimulatory effect on the secretion of gonadotropinreleasing hormone (GnRH). The pathophysiological importance of KiSS-1 and kisspeptin is well known, the developmental patterns of expression of KiSS-1 genes and serum level of kisspeptin have not been explored to date. We report the expression profile of KiSS-1 genes and serum level of kisspeptin in the rat at different developmental stages
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