Merkel cell carcinoma: A rare sarcoma

Abstract

Merkel cell carcinoma (MCC) is a rare cutaneous neoplasm that accounts for less than 1% of all primary cutaneous neoplasms. The majority of MCC cases (80%) are caused by Merkel cell polyomavirus (MCPyV) clonal integration into the host genome. In the remaining 20% of cases, UV mutations are responsible, and prolonged UV exposure is a factor. Herein, we present two cases of this rare tumor: a 48-year-old female with a diagnosis of hairy cell leukemia and an elderly male previously healthy. Key words: Merkel cell carcinoma, Cutaneous neoplasm, Hospital dermatology