Mercurial diuretics: some hazards of mercuhydrin; report of 2 cases with one death.

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Case Reports1 June 1950MERCURIAL DIURETICS: SOME HAZARDS OF MERCUHYDRIN; REPORT OF TWO CASES WITH ONE DEATHALFRED WALLNER, M.D., LAWRENCE HERMAN, M.D.ALFRED WALLNER, M.D.Search for more papers by this author, LAWRENCE HERMAN, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-32-6-1190 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptReports of unfavorable reactions following the administration of mercurial diuretics are becoming more common. Kaufman1 summarized 32 fatalities immediately following intravenous injection of mercurial diuretics. Molnar2 reported a death following intraperitoneal administration (mercupurin). Kline and Seymour3 noted severe reactions following the administration of mercurin intravenously or by rectal suppository. Waife and Pratt4 observed a patient who died in anuria following prolonged administration of mercupurin. The injection precipitating the reaction had been given intramuscularly. This is the only previously reported fatality following intramuscular administration.Reports of unfavorable systemic reactions to mercuhydrin have been limited to relatively few scattered observations. Modell, Gold...Bibliography1. Kaufman RE: Immediate fatalities after intravenous mercurial diuretics, Ann. Int. Med. 28: 1040-1047, 1948. LinkGoogle Scholar2. Molnar S: Plötzlicher Tod nach einer intraperitonealen Novurit-Injektion, Klin. Wchnschr. 14: 239-240, 1935. CrossrefGoogle Scholar3. KlineSeymour EMWB: Systemic reactions to mercurial diuretics, Am. J. M. Sc. 203: 874-879, 1942. CrossrefGoogle Scholar4. WaifePratt SOPT: Fatal mercurial poisoning following prolonged administration of mercurophylline, Arch. Int. Med. 78: 42-48, 1946. CrossrefGoogle Scholar5. 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Author, Article, and Disclosure InformationAffiliations: *Received for publication September 3, 1949.Published with the permission of the Chief Medical Director, Department of Medicine and Surgery, Veterans Administration, who assumes no responsibility for the opinions expressed or conclusions drawn by authors.From the Medical Service, Birmingham Veterans Administration Hospital, Van Nuys, California. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byQuecksilberhaltige DiureticaRenal Tubular Necrosis due to Nephrotoxicity of Organic Mercurial DiureticsRICHARD B. FREEMAN, M.D., JOHN F. MAHER, M.D., GEORGE E. SCHREINER, M.D., F.A.C.P., F. K. MOSTOFI, M.D.MetalleMetalleSYSTEMIC REACTIONS TO A MERCURIAL DIURETIC (MERCAPTOMERIN)Mercuhydrin sensitivityHypersensitivity to MercuhydrinGeneral Practice ReviewClinical Aspects of Mercurial Diuretics 1 June 1950Volume 32, Issue 6Page: 1190-1197KeywordsDiureticsIntravenous injectionsKidneysMedical servicesSuppositorySurgery ePublished: 1 December 2008 Issue Published: 1 June 1950 PDF downloadLoading ...