Abstract
People with psychosis have a high prevalence of problematic substance use that is generally thought to complicate their treatment. One explanation of the co-occurrence of psychosis and substance-use disorders is that people with psychosis more often than others use substances to ameliorate distress by regulating their affect and self-experience. Affect regulation is related to mentalization, which can be problematic for many people with psychosis. The aim of this study was to investigate the relationship between substance use, mentalization, and affect regulation in psychosis from an experience-based perspective. We interviewed 12 men with diagnoses of psychosis and a concurrent substance-use disorder about their mental health problems, life history, relationships, and substance use. We analysed the semi-structured interviews thematically and deductively, and organized the data into two main themes, each containing related sub-themes. The first theme concerned general ways of handling distress, which we o...
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