Abstract

Mental health difficulties and mental disorders are common in adolescents living with HIV or who are affected by HIV because of living in HIV-affected households in low- and middle-income (LMICs) countries, but little is known about the interventions that target these individuals and whether they are effective. This systematic review aims to address these gaps by examining what has worked and what has not worked to support the mental health of adolescents living with HIV or affected by HIV in low- and middle-income contexts (PROSPERO Number: CRD42018103269). A systematic literature review of online databases from the year 2000 to 2018, using Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, included English-language publications of quantitative evaluations of psychosocial interventions aiming to improve mental health among adolescents living with HIV and adolescents from HIV-affected households (aged 10-24 years) in LMICs. Out of 2956 articles, 16 studies from 8 LMICs met the inclusion criteria. Thirteen studies focused on adolescents affected by HIV and only three studies on adolescents living with HIV. Only five studies included were from Sub-Saharan Africa. Interventions most often used a family-strengthening approach strengthening caregiver-adolescent relationships and communication and some problem-solving in groups or individually. Five studies reported statistically significant changes in adolescent and caregiver mental health or mental well-being, five among adolescents only and two among caregivers only. Research on what works to improve mental health in adolescents living with HIV in LMIC is in its nascent stages. Family-based interventions and economic strengthening show promise.

Highlights

  • Mental health difficulties and mental disorders are common in adolescents living with HIV or who are affected by HIV because of living in HIV-affected households in low- and middle-income (LMICs) countries, but little is known about the interventions that target these individuals and whether they are effective

  • Research on what works to improve mental health in adolescents living with HIV in low- and middle-income countries (LMICs) is in its nascent stages

  • Keywords Adolescents living with AIDS; mental health; HIV/AIDS; interventions; systematic review

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Summary

Background

Mental health disorders among adolescents constitute a significant problem worldwide, with estimates ranging from 10 to 20%.1 the prevalence rates are less well-established in low- and middle-income countries (LMICs), estimates ranging from 13% in Brazil and India to 18% in Ethiopia and 15% in South Africa[2] indicate high prevalence rates. The relationship between mental health and HIV is modified by multiple family and contextual risk influences such as the role of the caregiver,[10] levels of impoverishment, violence, substance misuse and neighbourhood disintegration. These adolescents experience stigma by association with family members living with HIV, which can drive persistent mental health symptoms of anxiety and depression.[23] A systematic review of psychosocial interventions focusing on mental health resilience of young people affected by HIV showed that parenting and family support were important to their mental health and psychosocial adjustment.[8]

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Study design Cluster RCT
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