Abstract
Age, derived fat index (FI), and clinical score at the time of menarche were determined from records of 63 girls with cystic fibrosis (CF) and from 17 comparably aged but nonmenarchal girls with CF. The mean age of menarche in girls with CF was 14.5 years at a mean FI of 20.1% fat; thus, they were significantly older and had less fat than normal girls. Menarchal age was related to severity of illness. Amenorrheic girls with CF, mean age of 14 years, were significantly sicker and smaller. Gonadotropin and estradiol levels in 23 girls with CF were normal. The delay in menarche in CF appears to be closely related to severity of illness. Furthermore, although the relationship of puberty to body composition may or may not be coincidental, it is unlikely that puberty is initiated by a "critical body composition."
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
