Abstract

Emulsions or particles prepared from emulsion with size-uniformity and size-controllability present distinctive advantages in industrial applications, such as microcapsules in drug delivery, particulate adjuvants for vaccination, and microspheres media in chromatographic separation and cell culture. According to different principles of emulsion preparation, the membrane emulsification technology (MET) can be divided into two groups, the cross-flow membrane emulsification and the premix membrane emulsification, also called as direct membrane emulsification and rapid membrane emulsification. This chapter introduces the representative mechanisms of both cross-flow MET and premix MET and their developments over the years from macro to micro scales. It discusses the representative mechanisms and models involving cross-flow MET. The force balance model are the most universal explanation for various experimental phenomena and laws during membrane emulsification. Some processes that occur in cross-flow emulsification are also of relevance for premix emulsification design and process optimization.

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