Abstract
Antisera specific for human lymphoid cells in tissue culture were prepared. Rabbits were immunized with a lymphoid cell membrane fraction solubilized by papain and purified by physicochemical means. After appropriate absorption (with peripheral blood leukocytes of the same HL—A type) the antisera reacted with all established lymphoid cell cultures tested, but not with peripheral blood leukocytes.The antigen(s) reacting with these antisera seem to be unique for cells in culture and appear at the time the cell becomes an established cell line. The antigens were not detectable in normal PBL, non‐lymphoid human cell lines in tissue culture or in normal human serum or fetal calf serum, but were present in several leukemic cell samples.
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call