Medicinal Importance, Pharmacological Activities, and Analytical Aspects of an Isoflavone Glycoside Tectoridin

Abstract

Background: Polyphenols are a group of secondary plant metabolites produced in plants as a protective system against oxidative stress, UV radiation, pathogens, and predatorial attacks. Flavonoids are a major class of plant phenolics present in fruits, vegetables, tea, and red wine. Tectoridin, also called 40,5,7-thrihydroxy-6-methoxyisoflavone-7-Ob-D-glucopyranoside is an isoflavone glycoside present in the flower of Porites lobata. Methods: Present work focused on the biological importance, therapeutic potential, and pharmacological activities of tectoridin in medicine. Numerous scientific data have been collected from different literature databases such as Google Scholar, Science Direct, PubMed, and Scopus to know the health beneficial potential of tectoridin. Pharmacological data have been analyzed in the present work to know the biological effectiveness of tectoridin against human disorders. Analytical data of tectoridin have been collected and analyzed in the present work to know the importance of modern analytical methods in the isolation, separation, and identification of tectoridin. Results: Scientific data analysis revealed the biological importance and therapeutic benefit of tectoridin in medicine, signifying the therapeutic potential in healthcare systems. The biological activities of tectoridin are mainly due to its anti-inflammatory, anti-platelet, anti-angiogenic, hepatoprotective, anti-tumor, estrogenic, antioxidant, and hypoglycemic activity. However, this work has also presented the effectiveness of tectoridin against rat lens aldose reductase, nitric oxide, skeletal and cardiac muscle sarcoplasmic reticulum, and enzymes. Analytical data signified the importance of modern analytical techniques for separation, identification, and isolation of tectoridin. Conclusion: The present work signified the biological importance and therapeutic benefit of tectoridin in medicine and other allied health sectors.