Abstract
Ficus racemosa is a traditional medicinal plant found in Southeast Asia and Australia. It is commonly known as 'gular'or ‘Dumur’. Owing to the presence of β-sitosterol it decreases the blood glucose concentration. Many active constituents isolated from different parts of this plant exhibit useful pharmacological activity. The objective of this dissertation is to identify the biological activity of the roots of an indigenous medicinal plant, viz., Ficus racemosa (Family: Moraceae) and to evaluate the possible phytochemical and pharmacological profiles of the crude extracts. Some chemical and biological researches on this plant have been conducted out so far, focusing mainly on the plant's bark and root. That's why the objective of this framework is to assess the different possibilities of developing new therapeutic targets from this plant's fruit that could be crucial for the treatment of many diseases.
Highlights
1.1 Rationale and Objective of the Work Phytochemistry is a branch of Pharmacognosy, with chemical and biological characters, which study the obtaining of medicaments by natural or semi synthesis methods? The subject “Phytochemstry” deals with the chemical structures of secondary metabolites, their metabolism, and their distribution and biological functions [1]
4.3.2 Thrombolytic activity investigation Cerebral venous sinus thrombosis (CVST) is a common disorder that is often accompanied by significant morbidity and mortality
6.4 Results and discussion of In vitro antimicrobial screening of Ficus racemosa The Methanol extract of leaf of Ficus racemosa (MESF) and different partitionates i.e. Petroleum ether (PESF), carbon tetrachloride (CTCSF), chloroform (CSF) and aqueous (AQSF) soluble partitionate of the methanol extract of leaf of Ficus racemosa were subjected to antimicrobial screening with a concentration of 400 g/disc in every case
Summary
1.1 Rationale and Objective of the Work Phytochemistry is a branch of Pharmacognosy, with chemical and biological characters, which study the obtaining of medicaments by natural or semi synthesis methods? The subject “Phytochemstry” deals with the chemical structures of secondary metabolites, their metabolism, and their distribution and biological functions [1]. The purpose of this study was to evaluate different extractives of roots of Ficus racemosa as new potential sources of natural antioxidants and phenolic compounds today, many new chemotherapeutic agents are synthetically derived, based on "rational" drug design. Among the above mentioned techniques, the disc diffusion is a widely accepted in vitro investigation for preliminary screening of test agents which may possess antimicrobial activity [59] It is essentially a quantitative or qualitative test indicating the sensitivity or resistance of the microorganisms to the test materials. Inflammatory cells produce a complex mixture of cytokine growth and differentiation, as well as physiologically active arachidonate metabolites They possess the ability to generate reactive oxygen species (ROS) that can damage cell biomolecules, which in turn increase the inflammation status [64]. The aim of this study was to investigate the anti-inflammatory activity of the methanol extract and its different fractions of ficus racemosa fruit
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