Abstract
The growing interest in natural and biocompatible solutions has led to the development of medical devices based on natural bioactive substances offering safe and effective alternatives to synthetic products. This review examines the current state of research and technological advances in the field of medical devices based on plants and natural bioactive substances, focusing on their applications in wound healing and transdermal drug delivery. Wound-healing devices using plant extracts such as Centella asiatica and Curcuma longa are showing promising results in accelerating the repair of damaged tissue. In addition, transdermal delivery systems based on natural compounds enable controlled and targeted administration of active ingredients, increasing therapeutic efficacy while reducing side effects. The advantages of these devices include enhanced biocompatibility and biodegradability, as well as improved therapeutic efficacy. However, challenges remain, not least the regulatory aspect, especially with regard to the variability of natural compounds and the difficulties of standardisation. Ongoing research and rigorous clinical trials are needed to overcome these obstacles and maximise the clinical benefits of medical devices based on natural bioactive substances.
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