Abstract

Acinetobacter baumannii is ubiquitous in nature and classified as non-fermented gram-negative bacilli...

Highlights

  • Acinetobacter baumannii is ubiquitous in nature and classified as non-fermented gram-negative bacilli

  • Despite the gene is not identified in A. baumannii, speculations have arisen that the shift from MDR Acinetobacter to Pandrug-Resistance (PDR) cannot be avoided as a result of transmissible colistin resistance mechanisms that emerge [15]

  • A. baumannii has been underlined as a nosocomial pathogen capable of yielding a high level of resistance against different antibiotics

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Summary

Introduction

Acinetobacter baumannii is ubiquitous in nature and classified as non-fermented gram-negative bacilli. Most of the conducted studies such as new epidemiological surveys have suggested its emergence as the pathogenic bacteria of hospitalacquired pneumonia. Most of the known A. baumannii strains are either multidrug-resistant (MDR) or extensively drug-resistant (XDR) in nature [1]. Bacteria are subjected to genetic modifications in order to generate genes that are capable of overcoming antibiotic actions due to enhanced performance. Such modifications occur in a negligible amount of base pairs in the DNA, thereby resulting in one or multiple amino acids replacement in an essential target

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