Abstract
The aim of the study was to assess the clinical effects of periodontal healing using a Romanian pharmaceutical compound of marine fish extract (Alflutop®). Adults with periodontal disease were included in the study group. Gingival inflammation, the degree of tooth mobility, and probing depth (PD) were recorded for each patient before and after therapy. Patients were divided into two groups: group I—after scaling and root planing (SRP), patients followed therapy with marine fish extract, Alflutop®, group II—SRP therapy alone. Statistically significant differences between groups in terms of gingival inflammation reduction (p = 0.045) were found. Tooth mobility reduction, as well as PD improvement, were also noticed after the therapy (p = 0.001), but no statistically significant differences among PD reduction rates were found (p = 0.356). Alflutop® has proven a certain therapeutic efficiency in the treatment of periodontitis in terms of reduction in the clinical signs of inflammation and tooth mobility.
Highlights
Periodontal healing after specific anti-inflammatory and antimicrobial periodontal therapy can be supported by specific natural or synthetic compounds. This kind of therapy could be included as part of non-surgical therapy—and it is used after scaling and root planing (SRP)
The results showed the regenerative properties of Alflutop® used in endodontic temporary root canal treatment [18]
Sixty-five patients with periodontitis were divided into group I with 35 cases, mean patients with periodontitis were and divided into group30I controls, with 35 cases, agedSixty-five
Summary
Periodontal healing after specific anti-inflammatory and antimicrobial periodontal therapy can be supported by specific natural or synthetic compounds. The main objective of non-surgical periodontal regeneration treatment involves the obtainment of a biologically active complex of natural compounds [10,11,12] aimed at assisting periodontal healing. In this context, natural biological chemical compounds are increasingly preferred as treatment alternatives. One of these compounds is Alflutop® , a Romanian pharmaceutical bioactive concentrate of marine fish, from the Black Sea, which is widely used in the treatment of degenerative osteoarticular diseases, inflammatory rheumatism or post-traumatic osteitis [13]
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