Abstract
The electroretinogram (ERG) is considered interesting not only as a diagnostic information in the ophthalmological clinics but also in biological engineering as a clue to the opto-electric conversion mechanism in the retina. Conventionally, ERG is observed using the whole field stimulation of the retina by a strong flash, where the information concerning the local activities of the retina cannot be obtained. Another point in ERG is that the analysis is difficult due to the nonlinearity and the ambiguity of the stimulus waveform. This paper proposes a new method which analyzes the frequency characteristics of the micro-ERG (μ-ERG), evoked by the stimulation using the light-emitting diode (LED). This method has the following advantages: the stimulating waveform can be controlled arbitrarily; the method of linear system analysis can be applied; the local stimulation can be realized; and the color sensation can be examined. This paper discusses two basic techniques in the detection of the μ-ERG. One is the Fourier analysis of the synchronized ERG evoked by the sine wave stimulus, and the other is the correlation analysis using the random stimulus. The results of the two methods are compared, and the usefulness of the proposed method is indicated.
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