Measurement of interleukin-6 levels and some of the hematological factors in individuals that suffering from Crohn's disease in Iraq

Abstract

The Crohn’s disease (CD), which is state of recurrent systemic infections with gut symptoms that are related to immunological issues, this disease typically affects the digestive system. The CD is a type of Inflammatory bowel disease (IBD). Patients with CD have a genetic background and are affected by environmental variables and the gut microbiome. A blood sample of 30 patients from Iraq with CD and thirty samples of healthy people as control were taken in this study during the period from Jul 2022 to Dec 2022. Gastro-Enterology and Hepatology Hospital in Baghdad, Iraq is the place that the blood samples were taken from. Hematological test was performed on all samples and also measurement of IL-6 levels in serum. The results of this study show significant differences in hematological factors between patients and control also in levels of IL-6. The conclusion of this study is that interlukine-6 plays part in the progression of CD by neutrophils are drawn to the site of inflammation, and furthermore neutrophils cause more damage to the same site.