Effect of Some natural products against Ehrlich Ascites Carcinoma in mice: A Review

Abstract

Cancer is a serious disease and it is one of the main causes of death, and it is considered the second cause, after people who suffer from heart failure. Through the statistics, Breast cancer is one of the most common types of cancer, with a rate of 99% in women and 1% in men. It is very complex, and patients with this type of cancer may face numerous challenges during their treatment period. It was determined that the death rate from cancer had decreased by 1.5%, but it is expected to increase in the future due to an increase in cancer cases (breast, prostate). Ehrlich model is a cancer that grows inside a mouse. Its origin is spontaneous mammary carcinoma, and when it spreads within the mouse, it takes two forms, either ascitic or solid. Ehrlich's ascites carcinoma is a spontaneous breast cancer that has a very high importance in scientific research. It is undifferentiated and has a short life. This type of cancer was used for the first time in 1932, when it was used inside the mouse in the abdomen, and a type of fluid was obtained for this called ( Ehrlich's ascites) due to the liquid substance on which cancer cells depend and consider it food and a means for rapid tumor growth, EAC deficiency causes anemia and thus causes a decrease in red blood cells or hemoglobin, EAC causes an increase in urea and a decrease in creatinine, and EAC causes an increase in liver enzymes and a decrease in total protein.Natural products are the only and most effective products that lead to the development of drugs, especially anti-cancer drugs and anti-inflammatories. Through studies, it has become clear that natural products are a source of drugs.