Abstract
Spectral domain optical coherence tomography (SDOCT) has the capability of generating optical sectioning images at high depth resolution in vivo, which is helpful for the diagnosis of various disease. But when the voluntary and involuntary movement of the sample occurs during the acquisition time, the real structure of the sample will be distorted. So it is valuable to compensate the motion artifacts in SDOCT imaging to obtain high quality images. We demonstrated a self-reference method of detecting and compensating the axial motion artifacts in which the axial motion is first detected by comparing the topology of different layers in tissue and the motion artifacts is then compensated by shifting the pixel numbers with the value detected. Compared with the cross-correlation method in which the value of correlation between adjacent A-scans over the whole depth are needed, our method has the advantage of reducing imaging time because in our method only two positions along the depth direction are deeded. The method was demonstrated by first imaging a slide and then the mouse’s ear in vivo.
Published Version
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