Abstract

AbstractIn this paper a simple mathematical model for the process of hemodialysis is presented. This model is based on a system of two linear differential equations of first order with partly discontinuous coefficients that describe the time‐development of the concentrations of a certain toxin (like urea) in the intra‐ and extracellular part of the human body. The main result is the existence of periodic positive solutions of this system under the natural assumption that the generation of the toxin and its removal by hemodialysis are periodic processes. These periodic positive solutions are also computed numerically for a realistic choice of the coefficients of the modelling differential equations.

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