Abstract
<h2>Abstract</h2> Urinary excretion of oestriol, oestrone, and pregnanediol was measured at the 34th and 37th weeks of gestation in 35 healthy young primigravidæ having a normal pregnancy and in whom the onset of labour was spontaneous or induced 12 days or more past term. At the 34th week there was a significant correlation between the level of urinary oestriol and oestrone and gestation at the subsequent onset of labour; the higher the oestriol output or the lower the oestrone, the nearer was delivery. At the 37th week the relation between oestriol excretion and gestation at labour was still significant but at a lower level, and there was no correlation between oestrone and the time of delivery. No association was found between pregnanediol excretion at 34 or 37 weeks and the stage of gestation at which delivery eventually took place. These results support the concept of a foetal role in timing the onset of labour in human pregnancy.
Published Version
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