Abstract
Recent reports have revealed a high prevalence of small tumors in patients with untreated congenital adrenal hyperplasia due to 21-hydroxylase deficiency.1, 2 However, to our knowledge no case of long treated 21-hydroxylase deficiency complicated by a large adenoma has been reported in the literature. We report on a female patient with the simple virilizing form of 21-hydroxylase deficiency in whom a massive adrenal adenoma developed following 21 years of steroid treatment. CASE REPORT
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