Abstract
This paper describes the invitro characterization of the mass transfer behavior in a Cordis-Dow hollow fiber artificial kidney. The purpose of this investigation was to establish the behavior of the dialyzer device, apart from the patient-artificial kidney system, so as to serve as a reference by which invivo performance may be correlated to the particular design and operating parameters of the capillary artificial kidney. This characterization allows specific therapy based upon the variation of surface area, blood and dialysate flow rates, transmembrane pressure and the solute spectrum to be removed. The characterization also allows the optimization of therapy using present designs and direct improvement of future designs to more accurately duplicate natural kidney function.
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